BioCentury | Jan 22, 2015
Targets & Mechanisms

Pseudo-allergy exposed

...Hopkins University School of Medicine, Baltimore, Md. Sanofi (Euronext:SAN; NYSE:SNY), Paris, France Targets and Compounds LHR...
BioCentury | Jun 13, 2013
Distillery Therapeutics

Indication: Cancer

...that could be useful for treating cancer. In in vitro binding studies, the compound bound LHR-1...
...Kd value of about 1.8 µM. In human cancer cells, the compound inhibited proliferation of LHR-1-positive...
BioCentury | Apr 2, 2009
Distillery Therapeutics

Indication: Endocrine disease

...Licensing status Publication and contact information Endocrine disease Contraception; ovarian cancer Luteinizing hormone/choriogonadotropin receptor (LHCGR; LHR...
...menopause and/or could function as contraceptives. A library screen identified a potent terphenyl inhibitor of LHCGR...
...the compound identified a more potent carbamate derivative. In assays, the lead compound allosterically modulated LHCGR-ligand...
Items per page:
1 - 3 of 3