22:46 , Apr 16, 2019 |  BC Extra  |  Preclinical News

Mounting a mitochondrial attack to starve the inflammasome

While companies are directly inhibiting NLRP3 to treat a swath of inflammatory diseases, at least one academic group is shutting down the protein’s upstream mitochondrial triggers. The approach, from University of California San Diego researchers,...
08:00 , Feb 13, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Choline kinase-a (CHKA) In vitro studies identified a CHKA inhibitor that could help treat cancers. An asymmetrical, biscationic inhibitor of...