BioCentury | Aug 25, 2020
Finance

Seeing path for cholesterol-lowering program, Forbion launches start-up to house former Dezima molecule

...Dutch firm reinvests in CETP inhibitor five years after return from Amgen deal By Paul Bonanos...
...in its class fell short.This time, the firm has created a start-up to reacquire the CETP...
...– Cholesteryl ester transfer proteinPCSK9 – Proprotein convertase subtilisin/kexin type 9 Paul Bonanos Amgen Inc. Dezima Pharma B.V. Cholesteryl ester transfer protein (CETP) AMG...
BioCentury | May 15, 2019
Finance

Sofinnova Investments-led syndicate forms CV play CinCor with $50M, Roche castoff

...these therapeutic areas. The decision followed discontinuation of Type II diabetes program aleglitazar and high-profile CETP...
...million in a series B in 2017. Targets: ALDOS (CYP11B2) - Aldosterone synthase; CETP - Cholesteryl ester transfer protein...
BioCentury | Nov 3, 2017
Financial News

BioGeneration closes Ventures Fund III at EUR82M

...to $1.3 billion in milestones. Last month, Amgen announced it was discontinuing development of cholesteryl ester transfer protein (CETP...
...which it acquired in the Dezima deal, after Merck reported outcomes data for its own CETP...
BioCentury | Nov 2, 2017
Finance

Bigger in Benelux

...to $1.3 billion in milestones. Last week, Amgen announced it was discontinuing development of cholesteryl ester transfer protein (CETP...
...which it acquired in the Dezima deal, after Merck reported outcomes data for its own CETP...
BioCentury | Oct 31, 2017
Financial News

BioGeneration closes third fund

...to $1.3 billion in milestones. Last week, Amgen announced it was discontinuing development of cholesteryl ester transfer protein (CETP...
...which it acquired in the Dezima deal, after Merck reported outcomes data for its own CETP...
BioCentury | Oct 27, 2017
Clinical News

Amgen discontinues development of CETP inhibitor

...Amgen Inc. (NASDAQ:AMGN) discontinued internal development of cholesteryl ester transfer protein (CETP) inhibitor AMG 899 (TA-8995). The company said...
...Japan Product: AMG 899 , TA-8995 (formerly DEZ-001) Business: Endocrine/Metabolic Molecular target: Cholesteryl ester transfer protein (CETP) Description: CETP...
...Treat dyslipidemia Endpoint: NA Status: Development discontinued Milestone: NA Chris Lieu AMG 899 TA-8995 Amgen Inc. Mitsubishi Tanabe Pharma Corp. Cholesteryl ester transfer protein (CETP...
BioCentury | Oct 25, 2017
Company News

Amgen raises guidance, discontinues CETP inhibitor

...Amgen Inc. (NASDAQ:AMGN) bumped up its 2017 guidance and said it discontinued internal development of cholesteryl ester transfer protein...
...decision in light of recently reported outcomes data from Merck & Co. Inc. (NYSE:MRK) for CETP...
BioCentury | Oct 13, 2017
Clinical News

End of the road for Merck's anacetrapib

...regulatory approval of anacetrapib (MK-0859) to treat coronary heart disease (CHD). Anacetrapib is a cholesteryl ester transfer protein (CETP...
...before clinicians would consider using anacetrapib over generic ezetimibe (see BioCentury, Sept. 1 ). Merck's CETP...
...Inc. (NYSE:MRK), Kenilworth, N.J. Product: Anacetrapib ( MK-0859 ) Business: Cardiovascular Allison Johnson anacetrapib MK-0859 Merck & Co. Inc. Cholesteryl ester transfer protein (CETP...
BioCentury | Oct 12, 2017
Clinical News

End of the road for Merck's anacetrapib

...regulatory approval of anacetrapib (MK-0859) to treat coronary heart disease (CHD). Anacetrapib is a cholesteryl ester transfer protein (CETP...
...clinicians would consider using anacetrapib over generic ezetimibe (see BioCentury Extra, Aug. 29) . Merck's CETP...
...III trials (see BioCentury, Jul. 7) . Allison Johnson anacetrapib dalcetrapib evacetrapib MK-0859 torcetrapib Eli Lilly and Co. Merck & Co. Inc. Pfizer Inc. Roche Cholesteryl ester transfer protein (CETP...
BioCentury | Sep 1, 2017
Clinical News

Merck reports additional data for CETP inhibitor in CHD

...9% compared to placebo (1,640 vs. 1,803 events, p=0.004). Merck previously reported that the cholesteryl ester transfer protein (CETP...
...Co. Inc. (NYSE:MRK), Kenilworth, N.J. Product: Anacetrapib (MK-0859) Business: Cardiovascular Molecular target: Cholesteryl ester transfer protein (CETP) Description: CETP...
...or presumed ischemic stroke Status: Additional Phase III data Milestone: NA Chris Lieu anacetrapib MK-0859 Merck & Co. Inc. Cholesteryl ester transfer protein (CETP) European...
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