19:35 , Feb 13, 2019 |  BC Innovations  |  Distillery Therapeutics

Autoimmune disease

INDICATION: Osteoarthritis Patient sample and mouse studies suggest inhibiting the CH25H-RORA axis could help treat osteoarthritis. In patients, mRNA and protein levels of CH25H and RORA, two factors on the cholesterol metabolism pathway in chondrocytes,...
07:00 , Aug 11, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Autoimmune disease Autoimmune disease G protein-coupled receptor 183 (GPR183; EBI2); cholesterol 25 hydroxylase (CH25H) In vitro and mouse studies suggest antagonizing EBI2 could help treat...