22:11 , Apr 13, 2017 |  BC Innovations  |  Targets & Mechanisms

Cool and also collected

A Nature Medicine study published this week shows the immune-modulating peptide thymosin α1 provides unexpected improvements in the dysfunctional ion channel that causes cystic fibrosis, and could lead to a single agent therapy to compete...
07:00 , Jul 9, 2007 |  BC Week In Review  |  Clinical News

Lomucin talniflumate: Development discontinued

GENR stopped a double-blind, placebo-controlled Phase II trial and discontinued development of Lomucin after a data monitoring committee (DMC) said there would be no additional benefit to further enrollment in the study. GENR has an...
07:00 , Sep 26, 2005 |  BC Week In Review  |  Clinical News

Lomucin: Phase II started

GENR began a double-blind, placebo-controlled, European Phase II trial in 200 patients. Genaera Corp. (GENR), Plymouth Meeting, Penn.   Bago Group , Buenos Aires, Argentina   Product: Lomucin   Business: Pulmonary   Molecular target: hCLCA1...
07:00 , Apr 25, 2005 |  BC Week In Review  |  Clinical News

Lomucin: Phase II start

GENR will start this quarter a double-blind, placebo-controlled, European Phase II trial of Lomucin in 200 patients. Genaera Corp. (GENR), Plymouth Meeting, Penn.   Bago Group , Buenos Aires, Argentina   Product: Lomucin   Business:...
07:00 , Oct 20, 2003 |  BC Week In Review  |  Clinical News

Lomucin: Phase II

In a double-blind Irish Phase II trial in 55 patients, Lomucin improved FEV1 and FVC from baseline. Lomucin patients had a 0.04 liter improvement in FEV1 after 4 weeks, the primary endpoint, while placebo patients...
08:00 , Feb 25, 2002 |  BC Week In Review  |  Clinical News

Genaera preclinical data

Researchers published in the Journal of Allergy and Clinical Immunology that analysis of bronchial biopsy specimens from 19 volunteers with or without asthma showed that hCLCA1 mRNA expression is increased in epithelial cells from asthma...
08:00 , Dec 17, 2001 |  BC Week In Review  |  Company News

Genaera other research news

Researchers published in the American Journal of Respiratory Cell and Molecular Biology the identification of human CLCA1, which is the homolog of a murine gene that is upregulated in the lungs in an IL-9 transgenic...
07:00 , Apr 16, 2001 |  BC Week In Review  |  Company News

Takeda Chemical other research news

Researchers published in the Proceedings of the National Academy of Sciences the identification of gob-5, a gene encoding a calcium-dependent chloride channel , that is selectively expressed in the airway epithelial cells of a mouse...