08:00 , Jan 28, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Chemokine CC motif ligand 7 (CCL7; MCP3; SCYA6); CC chemokine receptor 3 (CCR3; CD193)

Cancer INDICATION: Prostate cancer Patient sample, cell culture and mouse studies suggest inhibiting CCL7-CCR3 signaling could help treat prostate cancer. In patients with prostate cancer, tumor levels of CCR3 correlated with disease recurrence or metastasis after tumor...
07:00 , Oct 24, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Amphiregulin (AREG); monocyte chemoattractant protein-1 (MCP-1; CCL2); chemokine CC motif ligand...
07:00 , Sep 26, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Myocardial infarction (MI) CD20; chemokine CC motif ligand 7 (CCL7; MCP3; SCYA6)...
07:00 , Sep 26, 2013 |  BC Innovations  |  Cover Story

Anti-CD20 therapy for heart attack

A multinational team has taken a new approach to treating heart attacks: depleting the host of B cells that recruit monocytes to the infarct site, where they further inflame and damage tissue.1 The mouse findings...
07:00 , Jun 23, 2011 |  BC Innovations  |  Cover Story

Origins of metastasis in breast cancer

Researchers at the Albert Einstein College of Medicine of Yeshiva University and the Centocor Ortho Biotech Inc. unit of Johnson & Johnson have linked multiple prometastatic processes in breast cancer to the production of the...
07:00 , Oct 8, 2009 |  BC Innovations  |  Tools & Techniques

An inflammatory vaccine

Researchers at The University of Texas M.D. Anderson Cancer Center have taken a new approach to DNA cancer vaccines: damaging host tissue to induce an inflammatory response and greater immune recognition of the antigen.1 The...