BioCentury | Oct 20, 2014
Emerging Company Profile

Rogne: Penetrating peptides

...serious infections. Rogne's RON2315 is a formulation of a 15-amino-acid sequence from chemerin . While chemerin...
...While chemerin typically activates inflammation, the peptide sequence is derived by proteolytic cleavage of chemerin...
BioCentury | Sep 1, 2014
Company News

University of Oxford, Rogne Bioscience deal

...exclusive, worldwide license to anti-inflammatory peptides. The deal includes C15 , a peptide derived from chemerin...
BioCentury | Aug 30, 2012
Distillery Therapeutics

Indication: Cancer

...In patients with melanoma, high levels of chemerin were correlated with increased survival. In mice, chemerin-expressing...
...the chemerin receptor Cmklr1 negated the chemoattractant's positive effects. Next steps include developing and evaluating chemerin-loaded...
BioCentury | Jan 31, 2011
Product Development

Safety in psoriasis

...surface of some plasmacytoid dendritic cells. It has one known natural ligand, called chemerin . Chemerin...
...lesions. Prochemerin is a substance produced by dermal fibroblasts, mast cells and endothelial cells. When chemerin...
BioCentury | Oct 9, 2008
Distillery Therapeutics

This Week in Therapeutics

...Summary Licensing status Publication and contact information Inflammation Allergy Chemokine (CC motif) receptor-like 2 (CCRL2); chemerin...
...less inflammation in response to sensitization and challenge than wild-type mice. Radioligand binding studies identified chemerin...
...the ligand for CCRL2. Next steps include studies evaluating small molecule or antibody inhibitors of chemerin-CCRL2...
BioCentury | Apr 17, 2008
Distillery Therapeutics

This Week in Therapeutics

...Publication and contact information Inflammation Inflammatory disease ChemR23 An SAR study identified a series of chemerin-derived...
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