23:18 , Mar 27, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Viral infection Cell culture studies suggest inhibiting the TCP1, CCT2, CCT3, CCT4, CCT5 or CCT8 subunits of TRiC could help treat reovirus infections. An siRNA screen in a reovirus-infected human brain microvascular endothelial cell...
07:00 , Sep 29, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: TCP1 containing ring complex (TRiC); T-complex 1 (TCP1; CCT1); chaperonin containing TCP1 subunit 3 (CCT3), CCT5; CCT7; CCT8; huntingtin (HTT)

Neurology INDICATION: Huntington's disease (HD) Mouse and cell culture studies suggest promoting expression of TCP1 , CCT3 and other TRiC subunits could help treat HD. In a synaptic formation assay utilizing co-cultured primary cortical and...