BioCentury | Oct 17, 2019

Small molecule disruption of Hsp90-CDC37 interaction for colorectal cancer

...growth in a xenograft mouse model of the disease. TARGET/MARKER/PATHWAY: Heat shock protein 90 (Hsp90); cell division cycle...
BioCentury | Aug 3, 2018
Finance

Lin’s new chapters

...oncology programs -- LBS-002, a brain-penetrating microtubule polymerization inhibitor for brain cancer; and LBS-007, a cell division cycle...
...finance that company in the U.S.,” said Financial Director Hao-Yuan Chuang. Hongjiang Li, Staff Writer LBS-002 LBS-007 LBS-008 Lin BioScience Inc. Cell division cycle...
BioCentury | Apr 18, 2018
Distillery Therapeutics

Cancer

...Next steps include identifying and testing CDC25 inhibitors in combination with undisclosed PI3K inhibitors. TARGET/MARKER/PATHWAY: Cell division cycle...
...of Toronto, Toronto, Ontario email: eldad.zacksenhaus@utoronto.ca Jaime De Leon University of Toronto Cell division cycle 25 homolog A (CDC25A) Cell division cycle 25B (CDC25B) Cell division cycle...
BioCentury | Apr 13, 2018
Targets & Mechanisms

Hello RNA

...inflammatory and male breast cancers. Fox Chase Cancer Center ; Queen's University Belfast 4593; 1225 Cell division cycle...
BioCentury | Mar 28, 2018
Distillery Techniques

Biomarkers

...expression levels of 32 of the genes, including centromere protein E (CENPE), cofilin 1 (CFL1), cell division cycle...
...Haider, The Institute of Cancer Research, London, U.K. email: Syed.Haider@icr.ac.uk Elizabeth S. Eaton The Institute of Cancer Research Cell division cycle...
BioCentury | Dec 8, 2017
Targets & Mechanisms

Epiphenomena at ASH

...the cancer. Washington University School of Medicine in St. Louis 2733 Histone cluster 1H1b (HIST1H1B) Cell division cycle...
...help treat diffuse large B cell lymphoma (DLBCL) and MCL. Vrije University Brussels (VUB) 2757 Cell division cycle...
BioCentury | Oct 27, 2017
Clinical News

Cancer Research UK begins Phase I of Lilly's CDC7 inihibitor in solid tumors

...maximum tolerated dose (MTD). Secondary endpoints include pharmacokinetics and progression-free survival (PFS). LY3143921 is a cell division cycle...
...Co. (NYSE:LLY). Eli Lilly and Co. (NYSE:LLY), Indianapolis, Ind. Product: LY3143921 Business: Cancer Molecular target: Cell division cycle...
...and progression-free survival (PFS) Status: Phase I started Milestone: NA Allison Johnson Cancer Research UK Eli Lilly and Co. Cell division cycle...
BioCentury | Apr 21, 2017
Product R&D

Making marks at AACR

...the *1*1 or *1*28 UGT1A1 haplotype. 3734 / 19 Takeda Pharmaceutical Co. Ltd. (Tokyo:4502) TAK-931 Cell division cycle...
BioCentury | Mar 24, 2017
Company News

Columbia University, Memorial Sloan Kettering, Lin BioScience deal

...exclusive, worldwide rights to LBS-007 and related IP. Lin said the small molecule that inhibits cell division cycle...
...Lin BioScience Inc. , Taipei, Taiwan Business: Cancer Alex Himes Columbia University Lin BioScience Inc. Memorial Sloan Kettering Cancer Center Cell division cycle...
BioCentury | Jan 3, 2017
Distillery Techniques

Drug platforms

...Cas9-specific inhibitor. In HEK cells expressing N. meningitidis Cas9 and a CRISPR single-guide RNA targeting cell division cycle...
...Alan R. Davidson, same affiliation as above email: alan.davidson@utoronto.ca Hongjiang Li University of Massachusetts Medical School University of Toronto Cell division cycle...
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