BioCentury | Sep 15, 2016
Distillery Therapeutics

Therapeutics: Activator protein-1 (AP-1; JUN); CDK5 regulatory subunit associated protein 1 (CDK5RAP1)

...Cell culture and mouse studies suggest AP-1 inhibitors could help treat Type II diabetes involving CDK5RAP1...
...mutations. In human pancreatic β cells generated from induced pluripotent stem (iPS) cells harboring mutant CDK5RAP1...
...pathway, in preclinical testing to treat traumatic brain injury (TBI). TARGET/MARKER/PATHWAY: Activator protein-1 (AP-1; JUN); CDK5 regulatory subunit associated protein 1 (CDK5RAP1)...
BioCentury | Sep 19, 2013
Tools & Techniques

Brain in a dish

Austrian researchers grabbed headlines last month when they coaxed cultured human induced pluripotent stem cells into forming brain tissue, 1 but in actuality the approach does not offer applications beyond studying very early brain development....
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