BioCentury | Apr 2, 2020
Distillery Therapeutics

CDC42BPA inhibition for high-grade serous ovarian carcinoma

...DISEASE CATEGORY: Cancer INDICATION: Ovarian cancer Inhibition of CDC42BPA alone or in combination with carboplatin and...
...HGSOC cell lines, an siRNA against CDC42BPA reduced proliferation by over 50%. Combination of the anti-CDC42BPA...
...testing CDC42BPA inhibitors in patient-derived xenograft (PDX) mouse models. TARGET/MARKER/PATHWAY: CDC42 binding protein kinase α (CDC42BPA...
BioCentury | Nov 17, 2016
Product R&D

Hemorrhaging targets

...Research Foundation (MMRF) 802 CDC42 binding protein kinase α (CDC42BPA) MM In MM cell lines, CDC42BPA...
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