18:55 , Aug 10, 2018 |  BC Week In Review  |  Financial News

Sensyne proposes London IPO

Data analysis company Sensyne Health Ltd. (Oxford, U.K.) proposed to raise £60 million ($78 million) in an IPO on the London Stock Exchange's AIM market. The company expects to begin trading on Aug. 17. Sensyne uses...
22:54 , Aug 7, 2018 |  BC Extra  |  Financial News

Sensyne proposes London IPO

Data analysis company Sensyne Health Ltd. (Oxford, U.K.) proposed to raise £60 million ($78 million) in an IPO on the London Stock Exchange's AIM market. The company expects to begin trading on Aug. 17. Sensyne uses...
18:12 , Aug 7, 2018 |  BC Extra  |  Company News

Icahn urges Cigna shareholders to oppose Express Scripts deal

Activist investor Carl Icahn sent a letter Tuesday urging shareholders of Cigna Corp. (NYSE:CI) to vote down its proposed acquisition of Express Scripts Holding Co. (NASDAQ:ESRX). Affiliates of Icahn own about 0.56% of Cigna's outstanding...
20:38 , Aug 6, 2018 |  BC Extra  |  Preclinical News

Modifying microbes for clot prevention

Cleveland Clinic researchers have developed inhibitors of bacterial choline trimethylamine-lyase (bacterial cutC), an enzyme found in commensal gut microbes, that could help treat thrombosis by targeting bacterial metabolic activity without killing the microbes. Previous studies identified...
19:29 , Aug 1, 2018 |  BC Innovations  |  Emerging Company Profile

Connecting the DotBodies

Cancer play DotBio Pte. Ltd. launched this week with a screening platform to discover and develop products based on humanized domain antibodies that could be more stable and easier to manufacture than other domain antibodies. DotBio...
00:47 , Jul 27, 2018 |  BC Innovations  |  Product R&D

Syncona’s sister act

With the final pieces of its gene therapy portfolio in place, Syncona Investment Management Ltd. thinks its five “sister companies” are poised to capitalize on recent regulatory and technological advances in gene therapy, and push...
23:57 , Jul 26, 2018 |  BC Innovations  |  Targets & Mechanisms

PureTech plumbs the brain

PureTech Health plc is backing a new way of thinking about Alzheimer’s disease that positions it primarily as a problem of poor drainage, building on the recent discovery of lymphatic vessels in the brain by...
23:04 , Jul 9, 2018 |  BC Extra  |  Financial News

Wellcome launches £250M blue sky fund

The Wellcome Trust launched the Leap Fund with £250 million ($333.5 million) to back life sciences projects deemed too risky to receive funding through traditional routes. Wellcome Director Jeremy Farrar told BioCentury the five-year, not-for-profit...
21:55 , Jul 2, 2018 |  BC Extra  |  Preclinical News

hESC-derived cells restore heart function after MI

A Nature Biotechnology study from University of Washington researchers suggests that cardiomyocytes derived from human embryonic stem cells could help restore heart function following myocardial infarction. The paper's authors wrote that the heart lacks robust regenerative...
00:51 , Jun 23, 2018 |  BioCentury  |  Strategy

Gawande’s Cheesecake Factory

Details about the healthcare organization Atul Gawande will run for Amazon.com Inc., Berkshire Hathaway Inc. and J. P. Morgan Chase & Co. are scarce -- basic facts, starting with its name, have not been disclosed....