BioCentury | Sep 29, 2016
Distillery Therapeutics

Therapeutics: CD300 molecule like family member F (CD300LF)

Infectious disease INDICATION: Norovirus Cell culture and mouse studies suggest inhibiting CD300LF could help treat norovirus infection. In mouse microglial cells infected with mouse norovirus, CD300LF knockout increased survival compared with normal CD300LF expression. In...
BioCentury | Sep 15, 2016
Targets & Mechanisms

Bon voyage!

For over 40 years, researchers have tried to grow norovirus in the lab without success. A Baylor College of Medicine group has cracked the problem by using 3-D cultures to discover exactly what cell type...
BioCentury | Aug 23, 2012
Distillery Therapeutics

Indication: Infectious disease

...antagonizing CD300A could help treat bacterial infections. In mice undergoing cecal ligation and puncture (CLP), Cd300a...
...bacterial clearance and survival than wild-type mice. In wild-type mice that underwent CLP, a mouse anti-Cd300a...
...survival compared with saline control. Next steps include clinical testing of an antibody against human CD300A...
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