01:50 , Sep 14, 2018 |  BC Innovations  |  Targets & Mechanisms

Repeat offenders

Dozens of intractable DNA repeat-driven diseases could boil down to a common problem: disrupted boundaries between chromatin domains, according to a study from the University of Pennsylvania. The results present new opportunities for diseases like...
23:03 , Jun 29, 2017 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

New Therapeutic Targets and Biomarkers: June 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during June 2017. Therapeutic targets are defined as any protein, gene or other...
21:00 , Jun 22, 2017 |  BC Innovations  |  Targets & Mechanisms

Exosomes deliver

Codiak BioSciences Inc. founder Raghu Kalluri has published the first animal data demonstrating exosomes can be used as drug delivery vehicles to treat cancer -- not just diagnose it. The findings also mark the unveiling...
07:00 , Mar 31, 2016 |  BC Innovations  |  Translation in Brief

Neighborhood loops

Specialized loop regions in chromosomes hold the keys to why and how some proto-oncogenes get activated to cause cancer, according to a group at the Whitehead Institute for Biomedical Research . The findings could provide...
08:00 , Jan 22, 2001 |  BC Week In Review  |  Company News

Ohio State University other research news

University researchers published in The Proceedings of the National Academy of Sciences that loss of imprinting (an epigenetic process that initiates differential expression of maternal or paternal allele) of insulin-like growth factor-2 (IGF-2) is strongly...