18:07 , May 15, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Alzheimer’s disease (AD) Patient sample and mouse experiments suggest that inhibiting CEBPB could help treat AD. In postmortem brain tissue samples from patients, levels of CEBPB were higher than in samples from unaffected subjects....
08:00 , Feb 2, 2012 |  BC Innovations  |  Cover Story

Browning fat

Dana-Farber Cancer Institute researchers have identified a new hormone dubbed irisin that is induced by exercise and triggers the conversion of white fat to brown-like fat in mice, leading to increased energy expenditure. 1 Ember...
08:00 , Feb 2, 2012 |  BC Innovations  |  Distillery Techniques

Technology: Assays & screens

Approach Summary Licensing status Publication and contact information Assays & screens Human induced pluripotent stem (iPS) cell-derived adipocytes to screen for obesity and diabetes therapeutics Human iPS cell-derived adipocytes could be used to identify therapeutics...
08:00 , Jan 14, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer CCAAT enhancer binding protein-b (CEBPB; CRP2); signal transducer and activator of transcription 3 (STAT3) A study in human samples and in mice suggests...
07:00 , Sep 17, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Multiple myeloma (MM) CCAAT/enhancer binding protein-b (CEBPB; C/EBPb) A study in cell culture suggests that inhibiting C/EBPb signaling could help treat MM. In three...