19:31 , Jan 24, 2018 |  BC Innovations  |  Emerging Company Profile

D over L for diabetes

ImmunoMolecular Therapeutics LLC’s small molecule inhibitor of an HLA-DQ8 peptide could treat Type I diabetes without courting the broad-spectrum immunosuppression of other disease-modifying therapies in development. About 60% of Type I diabetes patients carry the...
21:06 , Dec 8, 2017 |  BC Week In Review  |  Financial News

Lumicell raises $28.7M series C, reports breast cancer detection data

Cancer imaging company Lumicell Inc. (Wellesley, Mass.) raised $28.7 million on Dec. 7 in a series C round led by new investors Launch Capital and BlueIO. Existing investor Kodiak also participated, as did other undisclosed...
18:13 , Dec 8, 2017 |  BioCentury  |  Product Development

Making of Mepsevii

It may take a few years for Ultragenyx Pharmaceutical Inc. to recoup its investment in Mepsevii vestronidase alfa-vjbk, but the company expects to continue to reliably churn out treatments for ultra-rare diseases alongside a portfolio...
18:05 , Dec 7, 2017 |  BC Extra  |  Financial News

Lumicell raises $28.7M series C, reports breast cancer detection data

Cancer imaging company Lumicell Inc. (Wellesley, Mass.) raised $28.7 million in a series C round led by new investors Launch Capital and BlueIO. Existing investor Kodiak also participated, as did other undisclosed investors. Lumicell said...
20:41 , Oct 10, 2017 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: Gene profiling A panel of 17 genomic loci could help predict the risk of PD. Genome-wide association studies in a total of 20,084 PD patients and 397,324 healthy volunteers identified associations between the disease...
21:34 , Sep 29, 2017 |  BC Week In Review  |  Clinical News

Medivir reports Phase IIa data of MIV-711 for OA

Medivir AB (SSE:MVIR B) reported top-line data showing that MIV-711 slowed the degenerative effects of moderate osteoarthritis (OA) on both bone and cartilage of the knee in the Phase IIa MIV-711-201 trial. The company said...
20:52 , Sep 26, 2017 |  BC Extra  |  Clinical News

Medivir rises on Phase IIa OA data

Medivir AB (SSE:MVIR B) gained SEK14.75 (25%) to SEK74.75 on Tuesday after reporting that MIV-711 slowed the degenerative effects of moderate osteoarthritis on both bone and cartilage of the knee in the Phase IIa MIV-711-201...
00:36 , Sep 12, 2017 |  BC Extra  |  Preclinical News

Researchers identify 17 new PD risk loci

In a paper published in Nature Genetics , researchers from the Genentech Inc. unit of Roche (SIX:ROG; OTCQX:RHHBY), 23andMe Inc. (Mountain View, Calif.) and colleagues conducted a meta-analysis of genome-wide association studies (GWAS) and identified...
21:34 , Aug 3, 2017 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

New Therapeutic Targets and Biomarkers: July 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during July 2017. Therapeutic targets are defined as any protein, gene or other...
22:05 , Jul 25, 2017 |  BC Innovations  |  Distillery Therapeutics

Autoimmune disease

INDICATION: Lupus Mouse studies suggest inhibiting CTSS could help treat lupus. In a mouse model of the disease, CTSS levels were higher in dendritic cells from the spleen, blood and bone marrow than from the...