BioCentury | Aug 15, 2016
Product Development

No antigen left behind

Amgen Inc. partnered with Advaxis Inc. to develop a personalized neoantigen therapy platform with potential to invoke a broad immune response by both stimulating the immune system on multiple fronts and delivering the full repertoire...
BC Innovations | Nov 13, 2014
Cover Story

Boosting adjuvants

For all the talk of new vaccines, not much attention has been paid to the need for better adjuvants, which have remained stuck on alum-based products for decades. The NIH is committing up to $70...
BC Innovations | Aug 18, 2011
Distillery Therapeutics

Indication: Various

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Autoimmune disease; inflammatory disease Caspase recruitment domain family member 4 (CARD4; NOD1) An in vitro study identified inhibitors of NOD1 that...
BC Innovations | May 19, 2011
Distillery Therapeutics

Indication: Autoimmune disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Inflammatory bowel disease (IBD) BH3 interacting domain death agonist (BID); caspase recruitment domain family member 4 (CARD4; NOD1) In vitro...
BC Innovations | Apr 22, 2010
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Infectious disease Caspase recruitment domain family member 4 (CARD4; NOD1) In vitro and mouse studies suggest that activation of NOD1 could help treat mucosal...
BC Innovations | Jul 23, 2009
Distillery Therapeutics

Indication: Various

Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Autoimmune; inflammatory disease Baculoviral IAP repeat-containing 2 (BIRC2; cIAP1); baculoviral IAP repeat-containing 3 (BIRC3; cIAP2); caspase recruitment domain family member 4 (CARD4; NOD1); caspase recruitment...
BC Innovations | Dec 11, 2008
Distillery Therapeutics

This week in therapeutics

The Distillery: Therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Inflammatory bowel disease (IBD) Nucleotide-binding oligomerization domain containing 1 (NOD1; CARD4); chemokine (CC motif) receptor 6 (CCR6) Studies in mice suggest...
BC Innovations | Feb 28, 2008
Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Other Adjuvant Caspase recruitment domain family, member 4 (CARD4; Nod1); caspase recruitment domain family, member 15 (CARD15; Nod2) Studies in cell culture...
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