07:00 , Aug 20, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Caspase 12 (CASP12); programmed cell death 8 (AIFM1; AIF) Studies in cell culture and in mice identified a rocaglaol analog that could be useful...
07:00 , Sep 4, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Cancer Caspase-12; eukaryotic translation initiation factor 2, subunit 1a (EIF2S1; EIF2a); protein kinase regulated by RNA (PKR) Studies in cell...
00:04 , Apr 29, 2006 |  BC Extra  |  Clinical News

Researchers propose sepsis target

Researchers from The Scripps Research Institute and colleagues published in Nature that gene-targeted deletion of caspase-12 in mice confers resistance to peritonitis and septic shock. The researchers said the presence of caspase-12 exerts a dominant-negative...