BioCentury | May 14, 2015
Distillery Therapeutics

Therapeutics: Carbonic anhydrase I (CAI); CAII; CAIX; CAXII

...identified four lead compounds that inhibited the activity of CAI , CAII , CAIX and CAXII...
...anhydrase inhibitor, to treat glaucoma and ocular hypertension. TARGET/MARKER/PATHWAY: Carbonic anhydrase I (CAI); CAII; CAIX; CAXII...
BioCentury | Oct 31, 2013
Distillery Therapeutics

Indication: Cancer

...Publication and contact information Cancer Lung cancer Carbonic anhydrase XII (CAXII) Cell culture and mouse studies identified an anti-CAXII...
...CAXII activity with an IC50 of about 1 mg/mL. In two tumor cell lines, the anti-CAXII...
...cell proliferation compared with a control antibody. In mouse xenograft models of lung cancer, the anti-CAXII...
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