19:08 , Aug 3, 2018 |  BC Week In Review  |  Financial News

Impact raises $30M series C

Impact Therapeutics Inc. (Nanjing, China) raised $30 million in an untranched series C round led by new investor Decheng Capital. Existing investor Lilly Asia Ventures also participated. Impact is developing IMP4297, a PARP-1 inhibitor that is...
19:50 , Aug 2, 2018 |  BC Extra  |  Financial News

Impact raises $30M series C

Impact Therapeutics Inc. (Nanjing, China) raised $30 million in an untranched series C round led by new investor Decheng Capital. Existing investor Lilly Asia Ventures also participated. Impact is developing IMP4297, a PARP-1 inhibitor that is...
17:49 , Jun 28, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Staphylococcus Cell culture studies identified three cadmium-based supramolecule coordination complexes (SCCs) that could help treat methicillin-resistant Staphylococcus aureus (MRSA) infection. The three SCCs consist of hexagonal-shaped rings that incorporate 12, 18 or 24 cadmium (II)-terpyridine...
22:49 , Apr 10, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Bacterial infection Cell culture studies identified a dimeric lysine alkylamide-based compound that could help treat bacterial infection. Chemical synthesis and testing in bacterial cultures of dimeric lysine alkylamide analogs yielded a compound that inhibited the...
16:58 , Mar 22, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Colorectal cancer Patient sample, cell culture and mouse studies suggest inhibiting RIPK1 or MCU could help treat colorectal cancer. In patient samples, tumor levels of RIPK1 and MCU were higher than in adjacent normal...
23:17 , Sep 29, 2017 |  BioCentury  |  Strategy

Bridge to innovation

While Zai Lab Ltd. has joined the ranks of Chinese biotechs making a splash on NASDAQ, less noticed may be the first wave of China-based players moving into Boston to jump-start their push into novel...
20:01 , Mar 23, 2017 |  BC Innovations  |  Translation in Brief

Salmonella-1, tumors-0

A group led by researchers at Chonnam National University has shown that a non-virulent strain of Salmonella typhimurium expressing an immune-stimulating protein from another bacterial species shrank tumors, providing a bacteria-based immunotherapy that could potentially...
07:00 , Oct 17, 2016 |  BioCentury  |  Finance

First North's big fish

As the newest biotech on NASDAQ First North in Stockholm, InDex Pharmaceuticals Holding AB (SSE:INDEX) expects it will receive more attention from investors, as well as have less onerous and costly reporting requirements, compared with...
07:00 , Sep 29, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Macrophage stimulating protein (MSP; MST1); serine/threonine kinase 3 (STK3; MST2)

Gastrointestinal disease INDICATION: Colitis; hepatic; liver fibrosis Mouse studies suggest combined inhibition of MSP and STK3 could help treat colitis, liver damage and liver fibrosis. In a mouse model of chemical-induced colitis, a dual MSP/STK3 inhibitor tool...
07:00 , Aug 13, 2015 |  BC Innovations  |  Distillery Techniques

Techniques: SNPs on chromosome 10 as susceptibility loci for major depressive disorder (MDD)

Biomarkers TECHNOLOGY: SNPs Genetic sequencing studies identified two new susceptibility loci on chromosome 10 that could help predict risk of MDD. In 5,303 Han Chinese women with recurrent MDD and 5,337 non-depressed controls and validation in a...