17:39 , Dec 18, 2014 |  BC Innovations  |  Distillery Techniques

Techniques: Chromosome 11 open reading frame 30 (C11orf30),calpain small subunit 1 (CAPNS1; CAPN14), signal transducer and activator oftranscription 6 (STAT6)

Bio Markers TECHNOLOGY: Markers Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. In a discovery cohort of 603 EoE patients and 3,637 controls, variants at C11orf30...
07:00 , Nov 3, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Calpain small subunit 1 (CAPNS1; CAPN4) In vitro and rodent studies suggest inhibiting calpain could help treat pulmonary arterial hypertension (PAH). In smooth...
07:00 , Nov 3, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Autoimmune disease IL-17C; IL-17 receptor E (IL-17RE) Mouse studies suggest antagonizing IL-17C or its receptor, IL-17RE, could help treat autoimmune diseases. In mice with...