20:09 , Aug 1, 2018 |  BC Innovations  |  Distillery Therapeutics

Autoimmune disease; renal

INDICATION: Lupus; renal damage Patient sample and mouse studies suggest inhibiting CAMK4 could help treat lupus nephritis, focal segmental glomerulosclerosis (FSGS) and other podocytopathies. In kidney samples from lupus nephritis and FSGS patients, podocyte levels...
19:21 , Jul 31, 2017 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Alzheimer's disease (AD) Cell culture studies suggest inhibiting CAMK4 could help treat AD. In primary rat hippocampal neurons treated with β amyloid , levels of CAM4K activity were higher than in untreated neurons, and...
07:00 , May 1, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Lupus Calcium calmodulin-dependent protein kinase IV (CAMK4) Studies in human samples and mice suggest inhibiting CAMK4 could help treat lupus. T helper type 17...