BioCentury | Apr 16, 2021
Targets & Mechanisms

New targets featured at AACR signal growing opportunity in established mechanisms

...B1 receptorCD36 (GPIV)CDC40 –Cell division cycle 40CHP2 –Calcineurin...
BioCentury | Jan 24, 2021
Regulation

Lupus nephritis patients gain oral option as FDA approves Aurinia’s Lupkynis

...to $18.73 on Monday. Aurinia has already launched Lupkynis, a transisomer of cyclosporine A analog that inhibits calcineurin...
BioCentury | Jul 24, 2020
Product Development

July 23 Quick Takes: Priority Review for Aurinia; plus Jazz, CymaBay, Biogen, Vertex, Grünenthal, Mesoblast, BMS and Genfit

...Pharmaceuticals Inc. (NASDAQ:AUPH; TSX:AUP) to treat lupus nephritis. The PDUFA date for the immune-suppressing, IL-2-blocking calcineurin...
BioCentury | Jun 4, 2020
Product Development

With impending Benlysta submission, GSK seeking new paradigm in lupus nephritis treatment

...nephritis. It is seeking Priority Review of the transisomer of cyclosporine A analog that inhibits calcineurin...
BioCentury | Apr 30, 2020
Management Tracks

Desmond-Hellmann joins GV as adviser; plus Radius, Anika, AMAG, AiCure and more

...Miller, who was CFO and principal executive officer of Cerecor Inc. (NASDAQ:CERC). Aurinia is developing calcineurin...
BioCentury | Mar 7, 2020
Emerging Company Profile

Kira: depleting activated dendritic cells

...donor T cells to recognize host cells as foreign. Treatments for GvHD include corticosteroids and calcineurin...
...Janus kinase-2 Hongjiang Li, Staff Writer Kira Biotech Pty. Ltd. Bruton's tyrosine kinase (Btk) CD83 Janus kinase-2 (JAK-2) Janus kinase-1 (JAK-1) Calcineurin CD40 CD80...
BioCentury | Feb 29, 2020
Management Tracks

Brandicourt joins Alnylam's board: plus Bayer, Jazz, Halozyme, Arena, Aurinia, Adverum, Neoleukin, Centogene, Epirium, Insilico, Nouscom, Eloxx, Nordic, Summit,

...CCO and head of BD at Abeona Therapeutics Inc. (NASDAQ:ABEO). Aurinia is developing an immunosuppressant, calcineurin...
BioCentury | Dec 5, 2019
Company News

Dec. 4 Company Quick Takes: Allakos on the block?; plus Aurinia, Tecentriq, Gatehouse-AZ, Novartis-Amazon, Merck KGaA-Ping An and ICT

...study to treat lupus nephritis. Aurinia plans to submit an NDA to FDA for the calcineurin...
BioCentury | Jul 20, 2019
Emerging Company Profile

China Ophthalmology Focus eyes Asia market

...most advanced novel ophthalmology candidates are in Phase II testing, including a gel formulation of calcineurin...
BioCentury | Oct 25, 2018
Distillery Therapeutics

Neurology

...in the model, intrathecal administration of an anti-VEGF antibody, a tool compound VEGFR2 inhibitor or calcineurin...
...promoters of TRESK expression in models of metastasis-associated pain. TARGET/MARKER/PATHWAY: Potassium channel K2p18.1 (KCNK18; TRESK); calcineurin...
...online Oct. 16, 2018 doi:10.1126/scisignal.aao5150 CONTACT: Guo-Gang Xing, Peking University, Beijing, China email: ggxing@bjmu.edu.cn Sandi Wong VEGFR2 Peking University Calcineurin Potassium...
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