07:00 , Mar 17, 2008 |  BioCentury  |  Regulation

ITP pipeline

ITP pipeline Company Product Description Status Amgen (NASDAQ:AMGN) Nplate romiplostim Platelet growth factor peptibody engineered with Fc receptor Registration GlaxoSmithKline (LSE:GSK; NYSE:GSK)/ Ligand (NASDAQ:LGND) Promacta eltrombopag Non-peptide small molecule thrombopoietin (TPO) receptor agonist Registration 3SBio...
08:00 , Jan 31, 2005 |  BioCentury  |  Tools & Techniques

Microbodies at work

Evidence continues to accumulate that next-generation antibody therapeutics based on novel scaffolds work in vivo. Selecore GmbH has joined a small group of companies that have animal data demonstrating that the approach, which aims to...
07:00 , Jun 4, 2001 |  BC Week In Review  |  Clinical News

Alexion preclinical data

Alexion Pharmaceuticals Inc. (ALXN), Cheshire, Conn.   Product: Antibody agonist of c-Mpl receptor   Indication: Stimulate platelet proliferation   ALXN reported that a designed antibody that is an agonist to the c-Mpl receptor on the...
07:00 , Jun 4, 2001 |  BioCentury  |  Tools & Techniques

Antibody agonists

Say the word "antibody" and what comes to mind are words like "antagonist" and "blocker." But Alexion Pharmaceuticals Inc. reports that it has created what the company believes is the first designed antibody agonist, using...