19:52 , Oct 12, 2017 |  BC Innovations  |  Translation in Brief

Reservoir targets

As priorities in HIV drug development are shifting from suppressing viral replication to clearing the virus completely, attention has turned toward eliminating the latent viral reservoir. Toward that end, a group of Italian researchers has...
08:00 , Jan 21, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: BTB and CNC homology 2 (BACH2)

  Cancer INDICATION: Solid tumors Mouse studies suggest inhibiting BACH2 could help treat solid tumors. In mouse models of melanoma and lymphoma, BACH2 knockout increased tumor infiltration of interferon γ (IFNγ)-expressing CD4+ and CD8+ T cells and decreased...