03:19 , Nov 2, 2018 |  BC Innovations  |  Targets & Mechanisms

FDA’s pediatric target picks

FDA is looking ahead of industry in its guideline on targets for pediatric oncology, which includes more than 50 not yet in company pipelines in a list of over 220 the agency has its eye...
21:34 , Aug 3, 2017 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

New Therapeutic Targets and Biomarkers: July 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during July 2017. Therapeutic targets are defined as any protein, gene or other...
19:25 , Jul 31, 2017 |  BC Innovations  |  Distillery Techniques

Chemistry

TECHNOLOGY: Tool compounds A quinolin-2-one-based inhibitor of BRPF1 , BRPF3 and BRD1 could be useful for probing the roles of the proteins in cancer and inflammation. Chemical synthesis and in vitro binding and activity assays...
07:00 , Aug 15, 2014 |  BC Innovations  |  Distillery Therapeutics

Multiple sclerosis

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) BET bromodomain proteins In vitro and cell culture studies suggest selective inhibitors of BET bromodomain proteins could be useful for promoting...
07:00 , Aug 7, 2014 |  BC Innovations  |  Tools & Techniques

High throughput remyelination

Remyelinating compounds are highly sought after but have been difficult to identify in part because there is a dearth of high throughput screening platforms to detect remyelination. Researchers at the University of California, San Francisco...
07:00 , Jul 31, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) BET bromodomain proteins In vitro and cell culture studies suggest selective inhibitors of BET bromodomain proteins could be useful for promoting...