BioCentury | Nov 2, 2018
Targets & Mechanisms

FDA’s pediatric target picks

FDA is looking ahead of industry in its guideline on targets for pediatric oncology, which includes more than 50 not yet in company pipelines in a list of over 220 the agency has its eye...
BioCentury | Aug 3, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

...inflammation Cancer; inflammation Bromodomain containing 1 (BRD1; BRPF2) A quinolin-2-one-based inhibitor of BRD1, BRPF1 and BRPF3...
...cancer and inflammation. University College London Distillery Techniques Bromodomain and PHD finger containing 1 (BRPF1) Bromodomain and PHD finger containing 3 (BRPF3)...
BioCentury | Jul 31, 2017
Distillery Techniques

Chemistry

...TECHNOLOGY: Tool compounds A quinolin-2-one-based inhibitor of BRPF1 , BRPF3 and BRD1 could be useful for...
...and activity assays of quinolin-2-one analogs yielded a compound that bound the bromodomains of BRPF1, BRPF3...
...with vehicle. Next steps could include using the compound to probe the roles of BRPF1, BRPF3...
Items per page:
1 - 3 of 3