BioCentury | Nov 2, 2018
Targets & Mechanisms

FDA’s pediatric target picks

FDA is looking ahead of industry in its guideline on targets for pediatric oncology, which includes more than 50 not yet in company pipelines in a list of over 220 the agency has its eye...
BioCentury | Aug 3, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

...News Cancer; inflammation Cancer; inflammation Bromodomain containing 1 (BRD1; BRPF2) A quinolin-2-one-based inhibitor of BRD1, BRPF1...
...probing the roles of the proteins in cancer and inflammation. University College London Distillery Techniques Bromodomain and PHD finger containing 1 (BRPF1)...
BioCentury | Jul 31, 2017
Distillery Techniques

Chemistry

...TECHNOLOGY: Tool compounds A quinolin-2-one-based inhibitor of BRPF1 , BRPF3 and BRD1 could be useful for...
...binding and activity assays of quinolin-2-one analogs yielded a compound that bound the bromodomains of BRPF1...
...of BRPF1, BRPF3 and BRD1 in other cancers and inflammatory diseases. DESCRIPTION: An inhibitor of bromodomain and PHD finger containing 1 (BRPF1)...
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