22:24 , Jan 5, 2018 |  BioCentury  |  Finance

Scholar goes to the clinic

While Scholar Rock LLC’s series C round will bring the biotech’s lead program into the clinic, investors also want continued investment in the company’s growth factor modulation platform to maximize its value. On Jan. 3, Scholar...
16:54 , Jun 14, 2017 |  BC Innovations  |  Distillery Therapeutics

Musculoskeletal

INDICATION: Bone repair Pig studies suggest in situ ultrasound- and microbubble-mediated delivery of BMP6 gene therapy could help treat bone fractures. The therapy involved implanting a collagen scaffold at the fracture site to attract mesenchymal stem...
07:00 , Jul 16, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Peroxisome proliferation activated receptor (PPAR) γ

Musculoskeletal disease INDICATION: Osteoporosis Cell culture studies suggest an indole biphenyl carboxylic acid-based PPARγ antagonist could help treat osteoporosis. Optimization of a previously reported indole biphenyl carboxylic acid-based partial antagonist yielded an inverse agonist that inhibited PPARγ...
08:00 , Nov 21, 2013 |  BC Innovations  |  Targets & Mechanisms

Getting to the root of periodontitis

Current periodontitis therapies do not target the underlying immune response that drives the disease. A team from the U.S. and Brazil is looking to change that and has shown that microparticles loaded with chemokine CC...
07:00 , Sep 1, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Musculoskeletal disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Bone repair Bone morphogenetic protein 6 (BMP6) Rat studies suggest porcine adipose tissue-derived stem cells expressing...
08:00 , Mar 5, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Hematology

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Hematology ...