BioCentury | May 28, 2019
Distillery Therapeutics

TSPO agonist to treat Parkinson's disease

...Roche has TRO40303, a TSPO ligand, in Phase II testing for ischemia/reperfusion injury. TARGET/MARKER/PATHWAY: Peripheral benzodiazepine receptor...
...Schneider, German Center for Neurodegenerative Diseases, Bonn, Germany email: anja.schneider@dzne.de Chris Lieu German Center for Neurodegenerative Diseases Peripheral benzodiazepine receptor...
BioCentury | May 12, 2016
Distillery Therapeutics

Therapeutics: Peripheral benzodiazepine receptor (TSPO; PBR); Mdm2 p53 binding protein homolog (MDM2; HDM2)

...alone. Next steps could include testing the compound in animal models of glioblastoma. TARGET/MARKER/PATHWAY: Peripheral benzodiazepine receptor...
BioCentury | Mar 14, 2016
Emerging Company Profile

AMO's CNS ammunition

...is AMO-01 , a farnesylated dibenzodiazepinone in development for fragile X. AMO-01 targets the peripheral benzodiazepine receptor...
BioCentury | Jan 19, 2015
Company News

Trophos, Roche deal

...II testing to treat multiple sclerosis (MS). The pharma also gains TRO40303 , a peripheral benzodiazepine receptor...
BioCentury | Oct 7, 2013
Clinical News

TRO40303: Phase II ongoing

...Marseille, France Product: TRO40303 Business: Cardiovascular Molecular target: Peripheral benzodiazepine receptor (TSPO) (PBR) Description: Peripheral benzodiazepine receptor...
BioCentury | Jun 6, 2013
Distillery Therapeutics

Indication: Neurology

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Peripheral benzodiazepine receptor (TSPO...
BioCentury | Apr 29, 2013
Strategy

Zerhouni's progress report

...II Discontinued Nerispirdine (HP184) Potassium/sodium channel blocker Multiple sclerosis (MS) Ph II Discontinued SSR180575 Peripheral benzodiazepine receptor...
BioCentury | Nov 7, 2011
Clinical News

TRO40303: Phase II started

...Marseille, France Product: TRO40303 Business: Cardiovascular Molecular target: Peripheral benzodiazepine receptor (TSPO) (PBR) Description: Peripheral benzodiazepine receptor...
BioCentury | Mar 7, 2011
Clinical News

TRO40303: Phase I data

...Marseille, France Product: TRO40303 Business: Cardiovascular Molecular target: Peripheral benzodiazepine receptor (TSPO) (PBR) Description: Peripheral benzodiazepine receptor...
BioCentury | Oct 11, 2010
Clinical News

TRO40303: Phase I started

...Marseille, France Product: TRO40303 Business: Cardiovascular Molecular target: Peripheral benzodiazepine receptor (TSPO) (PBR) Description: Peripheral benzodiazepine receptor...
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