07:00 , Sep 1, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Transgenic BCL2-like 10 (BCL2L10; BLC-B)-expressing mouse model of multiple myeloma (MM)

Disease models TECHNOLOGY: Transgenics and knockouts Transgenic mice expressing human BCL2L10 could be useful for screening therapies to treat MM. Levels of BCL2L10 were higher in plasma B cells from MM patients than in B...
08:00 , Nov 18, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer B cell lymphoma (BCL) B cell CLL lymphoma 6 (BCL6); heat shock protein 90 (Hsp90); histone deacetylase (HDAC) In vitro and mouse studies suggest that...
08:00 , Dec 3, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer B cell lymphoma (BCL) B cell CLL/lymphoma 6 (BCL6); heat shock protein 90 (Hsp90) A study in mice suggests that Hsp90 inhibitors could help treat...