18:16 , Aug 16, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Prostate cancer Patient sample and cell culture studies suggest inhibiting BAG1 isoform L1 (BAG1-L1) could help treat prostate cancer. In patient samples, high BAG1-L1 levels in tumor cell nuclei were associated with disease progression....
07:00 , Sep 29, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Panel of 12 hippocampal proteins to diagnose early stage Alzheimer's disease

Biomarkers TECHNOLOGY: Tissue markers Hippocampal expression of a panel of 12 proteins could help diagnose early stage AD. Microarray analyses of postmortem brain tissue samples from six individuals previously not diagnosed with AD identified associations...
08:00 , Jan 14, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: BCL2-associated athanogene 3 (BAG3; CAIR-1)

Cancer INDICATION: Pancreatic cancer In vitro and mouse studies suggest inhibiting BAG3 could help treat pancreatic ductal adenocarcinoma (PDAC). In human PDAC cell lines co-cultured with human or mouse macrophages, BAG3 secreted by the cancer...
07:00 , Apr 15, 2013 |  BioCentury  |  Emerging Company Profile

Abcodia: Banking on biomarkers

Abcodia Ltd. is using blood samples that have been taken annually by the U.K. Collaborative Trial for Ovarian Cancer Screening to identify serum biomarkers that can detect breast, lung, pancreatic and colorectal tumors at least...
07:00 , Apr 30, 2012 |  BC Week In Review  |  Company News

Abcodia, Biouniversa deal

The companies partnered to develop Biouniversa's Biouniversa BCL2-associated athanogene 3 ( BAG3 ; CAIR-1 ) ELISA assay technology to detect pancreatic cancer in asymptomatic individuals and at the earliest stages. The partners will use Abcodia's...
07:00 , Apr 22, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer BCL2-associated athanogene 3 (BAG3); NF-kappa B (NF-kB) In vitro and mouse studies suggest that inhibiting BAG3 could help treat cancer. In human osteosarcoma cells,...