BC Innovations | Apr 18, 2019
Distillery Therapeutics

Lanthipeptide-based antibiotics for Gram-positive bacterial infections

DISEASE CATEGORY: Infectious disease INDICATION: Gram-positive bacterial infection; Staphylococcus; Enterococcus; Streptococcus Cell culture studies identified multiple lanthipeptide-based antibiotics that could help treat Gram-positive bacterial infections. Screening in cell-based growth assays of a library of compounds...
BC Innovations | May 25, 2018
Product R&D

Peptides step up

New screening platforms and synthetic approaches could finally solve some of the longstanding hurdles to turning antimicrobial peptides into therapeutic candidates to combat antibacterial resistance, overcoming their history of limited clinical efficacy, systemic toxicity and...
BC Innovations | Jan 22, 2015
Distillery Therapeutics

Therapeutics: Bacterial lipid II; bacterial lipid III

Infectious disease INDICATION: Gram-positive bacterial infection In vitro and mouse studies suggest a new antibiotic called teixobactin identified from soil bacteria Eleftheria terrae could help treat Gram-positive bacterial infections. In a panel of pathogenic bacteria,...
BC Innovations | Jan 9, 2014
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Sepsis Bacterial lipid II In silico, in vitro and mouse studies suggest a compound that mimics the antimicrobial peptide defensin a1 (DEFA1; HNP-1) could...
Items per page:
1 - 4 of 4