BioCentury | Apr 13, 2018
Targets & Mechanisms

Hello RNA

BioCentury’s analysis of new and emerging targets presented at this year’s AACR meeting reveals a surge in activity in non-coding RNAs, as researchers continue to expand target space. The results also reflect the ongoing high...
BioCentury | Jun 19, 2014
Distillery Techniques

Technology: Disease models

...contact information Disease models Mouse model of Crohn's disease Mice with the T300A mutation in autophagy related 16-like 1 (Atg16l1)...
...disease and evaluating therapeutic candidates. In the mouse model, knock-in of a Crohn's disease-associated T300A Atg16l1...
...led to greater intestinal bacterial replication and higher proinflammatory cytokine production than expression of wild-type Atg16l1...
BioCentury | Jan 25, 2007
Clinical News

Researchers link genetic variant to Crohn's disease

...protein ATG16L1 is significantly more likely to be present in individuals with Crohn's disease. Because ATG16L1...
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