07:00 , Apr 7, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: ATPase Ca++ transporting plasma membrane 4 (ATP2B4; PMCA4)

Cardiovascular disease INDICATION: Cardiomyopathy Mouse studies suggest inhibiting ATP2B4 could help treat hypertrophic cardiomyopathy (HCM). In a cardiac pressure overload mouse model of HCM, cardiac fibroblast-specific ATP2B4 knockout decreased heart size and weight compared with...
07:00 , Sep 13, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria ATPase Ca++ transporting plasma membrane 4 (ATP2B4; PMCA4); MARVEL domain containing 3 (MARVELD3) Genomewide association studies identified two loci associated with risk of...