07:00 , Aug 11, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: ATP-binding cassette sub-family G WHITE member 1 (ABCG1)

Cardiovascular disease INDICATION: Atherosclerosis Patient sample and mouse studies suggest inhibiting ABCG1 could help treat atherosclerosis. In blood from patients undergoing cardiac catheterization, high levels of ABCG1 in Treg cells correlated with low Treg numbers. In a...
07:00 , Mar 26, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: ATP-binding cassette sub-family G WHITE member 1 (ABCG1)

Cancer INDICATION: Cancer In vitro and mouse studies suggest ABCG1 inhibition could help treat cancer. In co-cultures of mouse tumor-associated macrophages and human cancer cell lines, ABCG1 deficiency in macrophages biased them toward an M1 phenotype and...
07:00 , Jun 17, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Endocrine disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine disease Diabetes ATP-binding cassette sub-family G WHITE member 1 (ABCG1); peroxisome proliferation-activated receptor-g (PPARG; PPARg) In vitro...