BioCentury | Feb 22, 2020
Product Development

Regenerative medicine for hearing loss makes quiet progress

...differentiation all converge on a single pathway that leads to upregulation of the transcription factor ATOH1...
...of which are clinical. Source: BCIQ: BioCentury Online Intelligence, company websites. Targets ATOH1 (HATH1) - Atonal homolog 1...
...Inc. Audion Therapeutics B.V. Quark Pharmaceuticals Inc. Acousia Therapeutics GmbH Sound Pharmaceuticals Inc. Otologic Pharmaceutics Inc. Brain-derived neurotrophic factor (BDNF) Atonal homolog 1 (ATOH1) (HATH1) Glycogen...
BioCentury | Dec 14, 2018
Product R&D

Gene therapy’s make or buy choice

...respectively. Novartis has ex-U.S. rights to Spark’s Luxturna. It also has CGF166, which delivers the ATOH1...
...Md. Vanrx Pharmasystems Inc., Burnaby, B.C. Xoma Corp. (NASDAQ:XOMA), Berkeley, Calif. Targets ATOH1 (HATH1) - Atonal homolog 1...
BioCentury | Apr 13, 2018
Company News

Novartis to acquire AveXis for $8.7B

...CGF166 is a recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1; HATH1...
...compound #), nusinersen (Generic), Spinraza (Informal) AveXis Inc. Biogen Bioverativ Inc. Celgene Corp. Homology Medicines Inc. Juno Therapeutics Inc. Novartis AG Sanofi Atonal homolog 1 (ATOH1) (HATH1) Retinaldehyde...
BioCentury | Apr 9, 2018
Company News

Novartis to acquire AveXis for $8.7B

...CGF166 is a recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1; HATH1...
BioCentury | Jun 2, 2017
Product Development

Ears wide open

...a recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 ( ATOH1 ; HATH1...
...Inc. (NASDAQ:GNVC) that uses a recombinant adenovirus 5 (Ad5) vector to deliver the atonal homolog 1 (ATOH1; HATH1...
...Hughes Medical Institute , Baylor College of Medicine and University of Illinois at Chicago that ATOH1...
BioCentury | Jan 27, 2017
Company News

GenVec, Intrexon deal

...is a recombinant adenovirus 5 (Ad5) vector containing cDNA carrying the atonal homolog 1 ( ATOH1 ; HATH1...
...Gaithersburg, Md. Intrexon Corp. (NYSE:XON), Germantown, Md. Business: Gene/Cell therapy, Other Chris Lieu CGF166 GenVec Inc. Intrexon Corp. Atonal homolog 1 (ATOH1) (HATH1...
BioCentury | Jan 11, 2017
Product R&D

Now hear this

...gene therapy to restore hearing. GenVec Inc. has CGF116, a gene therapy that delivers the ATOH1...
...Partners HealthCare Systems Inc., Boston, Mass. Teleflex Inc. (NYSE:TFX), Limerick, Pa. Targets ATOH1 (HATH1) - Atonal homolog 1...
BioCentury | May 9, 2016
Clinical News

CGF166: Phase I/II restarted

...Atonal homolog 1 (ATOH1) (HATH1) Description: Recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1...
...ATOH1) (HATH1) Description: Recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1; HATH1...
BioCentury | May 3, 2016
Clinical News

Hearing loss trial of GenVec gene therapy clears hurdle

...a recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 ( ATOH1 ; HATH1...
BioCentury | Feb 1, 2016
Clinical News

CGF166: Phase I/II suspended enrollment

...Atonal homolog 1 (ATOH1) (HATH1) Description: Recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1...
...ATOH1) (HATH1) Description: Recombinant adenovirus 5 (Ad5) vector containing a cDNA carrying the atonal homolog 1 (ATOH1; HATH1...
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