07:00 , Apr 9, 2009 |  BC Innovations  |  Distillery Therapeutics

This week in therapeutics

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Anterior pharynx defective 1 homolog B (APH1B) A study in cell culture and in mice suggests that...
07:00 , Jul 31, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker /pathway Summary Licensing status Publication and contact information Neurology Schizophrenia g-secretase; anterior pharynx defective 1 homologB (Aph1B); neuregulin 1 (Nrg1) A mouse study suggests that modulating g-secretase activity could...
07:00 , Jul 31, 2008 |  BC Innovations  |  Targets & Mechanisms

Cleaving Schizophrenia

A study published in the Proceedings of the National Academy of Sciences points to g-secretase, a major Alzheimer's disease target, as a new player in schizophrenia. 1 Although AD work has focused on g-secretase antagonists,...