08:00 , Nov 5, 2015 |  BC Innovations  |  Distillery Techniques

Techniques: Platelet-specific anoctamin 6 (ANO6; TMEM16F)-knockout mouse model of Scott syndrome

Disease models TECHNOLOGY: Transgenics and knockouts A mouse model of platelet aggregation with platelet-specific ANO6 knockout could be used to screen for therapies to treat Scott syndrome, a mild bleeding disorder. In Scott syndrome patients,...
07:00 , Oct 11, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Blood clots Anoctamin 6 (ANO6; TMEM16F) Mouse and cell culture studies suggest inhibiting TMEM16F could help prevent thrombosis. In mice, knocking out Tmem16f increased...