08:00 , Nov 12, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Anaphase promoting complex (ANAPC)

Cancer Cell culture studies suggest partially inhibiting ANAPC could help treat cohesion-defective cancers. In multiple human cancer cell lines, ANAPC knockdown induced more death in cells with cohesion defects than in cells with normal cohesion. In...
07:00 , Oct 28, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Anaphase promoting complex (ANAPC) An in vitro study suggests that a small molecule that inhibits the...
07:00 , Jun 11, 2009 |  BC Innovations  |  Targets & Mechanisms

K-Ras' Achilles' heel

Three research teams associated with Harvard Medical School have identified key proteins and pathways that K-Ras-driven tumors require for survival, providing points to disrupt the proliferation of cells that harbor drug-resistant mutations of the oncogene....
07:00 , Jun 11, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer ...