07:00 , Jun 30, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Meis homeobox 2 (MEIS2)

Cancer INDICATION: Acute myelogenous leukemia (AML) Patient sample and cell culture studies suggest inhibiting MEIS2 could help treat AML harboring the AML1-ETO oncogenic fusion protein. In AML1-ETO-positive patient samples, MEIS2 mRNA levels were higher than in AML...
07:00 , May 23, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) AML1-ETO oncogenic fusion protein; cyclooxygenase-2 (COX-2) In vitro and mouse studies suggest COX-2...
07:00 , Aug 11, 2011 |  BC Innovations  |  Cover Story

Bromodomain brake on AML

A Cold Spring Harbor Laboratory-led team has shown that a bromodomain inhibitor can help treat acute myeloid leukemia in mice, greatly expanding the therapeutic potential forthis emerging drug class.1 Newly founded Tensha Therapeutics Inc. haslicensed...
07:00 , Aug 4, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) E1A binding protein p300 (EP300; p300); AML1-ETO oncogenic fusion protein Cell culture...
08:00 , Feb 17, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) AML1-ETO oncogenic fusion protein; stem cell factor receptor tyrosine kinase (c-Kit; KIT; CD117)...
07:00 , May 13, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) AML1-ETO oncogenic fusion protein In vitro and mouse studies suggest that preventing...
07:00 , May 7, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer ...