BioCentury | Apr 28, 2017
Emerging Company Profile

Cutting cravings

...currently underserved by therapeutics, including alcohol abuse and cocaine and opioid addiction. The compound inhibits aldehyde dehydrogenase 2 family mitochondrial...
...said Amygdala is seeking additional capital. COMPANY PROFILE Amygdala Neurosciences Inc. Palo Alto, Calif. Technology: Aldehyde dehydrogenase 2 family mitochondrial...
...THP, a cocaine use-dependent inhibitor of dopamine synthesis." Nature Medicine (2010) Virginia Li, Staff Writer ANS-6637 Amygdala Neurosciences Inc. Aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Feb 17, 2017
Company News

Gilead, Amygdala deal

...Phase II trials this year of GS-6637 in alcohol and cocaine addiction. GS-6637 is an aldehyde dehydrogenase 2 family mitochondrial...
...City, Calif. Amygdala Neurosciences Inc. , Palo Alto, Calif. Business: Neurology Chris Lieu GS-6637 Amygdala Neurosciences Inc. Gilead Sciences Inc. Aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Feb 16, 2017
Company News

Amygdala acquires addiction candidate from Gilead

...this year of the candidate to treat cocaine and alcohol use disorders. GS-6637 is an aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Sep 25, 2014
Distillery Therapeutics

Indication: Neurology

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain Aldehyde dehydrogenase 2 family mitochondrial (ALDH2) Rodent studies suggest...
BioCentury | Aug 26, 2014
Financial News

Aldea closes $24 million B round

...plans to start Phase I testing of both an oral and IV formulation of the aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Jun 19, 2014
Distillery Therapeutics

Indication: Cancer

...inhibitors in mouse models of other cancers. Tekmira Pharmaceuticals Corp. has TKM-ALDH2, an siRNA targeting aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Mar 19, 2012
Clinical News

Alnylam, Tekmira preclinical data

...In animals, Tekmira's TKM-ALDH2 reduced liver aldehyde dehydrogenase 2 family mitochondrial (ALDH2) protein to undetectable levels (<2%) and increased blood...
BioCentury | Dec 1, 2011
Targets & Mechanisms

Taken to heart

...with a gradual loss of effectiveness. The development of tolerance is due to inactivation of aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Nov 17, 2011
Distillery Therapeutics

Indication: Cardiovascular disease

...Summary Licensing status Publication and contact information Cardiovascular disease Angina; myocardial infarction (MI); heart failure Aldehyde dehydrogenase 2 family mitochondrial...
BioCentury | Aug 26, 2010
Distillery Therapeutics

Indication: Neurology

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Addiction Aldehyde dehydrogenase 2 family mitochondrial (ALDH2) In vitro and...
Items per page:
1 - 10 of 12