BC Innovations | Mar 19, 2019
Distillery Therapeutics

Pan-ALDH1A inhibitor for ovarian cancer

DISEASE CATEGORY: Cancer INDICATION: Ovarian cancer In vitro , cell culture and mouse studies identified a pan-ALDH1A inhibitor that could help treat ovarian cancer. Chemical synthesis and in vitro testing of diethylaminobenzaldehyde analogs yielded a compound...
BC Innovations | Nov 15, 2016
Distillery Therapeutics

Cancer

INDICATION: Brain cancer Patient sample, cell culture and mouse studies suggest inhibiting FOXD1 or ALDH1A3 could help treat glioma. In patients, high tumor expression of FOXD1 or ALDH1A3 was associated with poor survival. In human...
BC Innovations | May 30, 2013
Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Aldehyde dehydrogenase 1 family member A3 (ALDH1A3) Patient sample and mouse studies suggest inhibiting ALDH1A3 could help treat a...
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