BioCentury | Oct 17, 2020
Translation in Brief

SARS-CoV-2 infects brain choroid plexus, compromises CSF-blood barrier; plus Passage’s GM1 gangliosidosis gene therapy, a new COVID-19 reporter and more

...cell activity and checkpoint inhibitor efficacy.A human albumin...
...Ferrara scientists described in Science Translational Medicine engineering human albumin...
...mucosal drug delivery. They showed that human albumin...
BioCentury | Aug 21, 2020
Product Development

Pfizer, BioNTech unveil data that gave partners their lead vaccine

...of the spike RBD with ELI-004, an adjuvant from Elicio’s Amphiphile platform. Amphiphile attaches antigens to an albumin-binding...
BioCentury | Aug 19, 2020

Momenta’s shift to innovative pipeline pays off with $6.5B J&J takeout

...doses, with variable intervals between courses.Some concerns about nipocalimab’s safety, specifically those related to serum albumin...
BioCentury | Jul 29, 2020
Distillery Therapeutics

Inhibiting proteolytic activation of the receptor PAR2 for eosinophilic esophagitis

...compared with samples from donors without the disease. In a mouse model of chicken egg albumin-induced...
BioCentury | Jul 23, 2020
Emerging Company Profile

On track for 2021 launch, Seer unveils unbiased proteomics tech and latest $55M round

...up low abundance proteins like cytokines, while not being saturated by highly expressed ones like albumin...
BioCentury | Jun 1, 2020

Intellia deal expands Regeneron’s reach into CRISPR therapies

...corrected Factor IX gene -- the gene lost in hemophilia B patients -- into the albumin...
BioCentury | May 23, 2020
Product Development

Hot topics at ASCO 2020

...I data from HPN424, a Tri-specific T cell Activating Construct (TriTAC) targeting PSMA, CD3 and albumin...
BioCentury | May 19, 2020
Emerging Company Profile

Helmed by OrbiMed’s Wang, Inmagene debuts with Phase II autoimmune program

...albumin-binding domain to extend serum stability and tissue distribution. According to Affibody, both IL-17a and albumin...
...of a Sustainable Market ”). COMPANY PROFILE Inmagene Biopharmaceuticals Shanghai, China Technology: Bispecific against IL-17, albumin...
BioCentury | Mar 9, 2020

With $22M B round, Numab to build out multispecific mAb pipeline

...Chinese rights to lead program ND021. The trispecific mAb targets PD-L1, 4-1BB and human serum albumin...
BioCentury | Feb 14, 2020
Targets & Mechanisms

Entrepreneur watch: Iwasaki targets the lymphatic system to clear brain tumors

...Her group found intranasal delivery of MHC Class II peptides increased blood-brain barrier permeability to albumin...
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