BioCentury | May 18, 2018
Company News

U of Birmingham spins out RA newco

...develop compounds around the peptide inhibitor of trans-endothelial migration (PEPITEM), a key regulator of the adiponectin (ADIPOQ)...
...research group led by University of Birmingham Professor of Chronic Inflammation Ed Rainger discovered the ADIPOQ...
BioCentury | May 14, 2018
Company News

U of Birmingham spins out RA newco

...develop compounds around the peptide inhibitor of trans-endothelial migration (PEPITEM), a key regulator of the adiponectin (ADIPOQ)...
...research group led by University of Birmingham Professor of Chronic Inflammation Ed Rainger discovered the ADIPOQ...
...the West Midlands Academic Health Science Network and the university's Enterprising Birmingham Fund. Jennie Walters University of Birmingham Adiponectin (ADIPOQ)...
BioCentury | May 18, 2017
Product R&D

Making cells compute

...combination of TNFα and IL-22 , and in response corrected the pathogenic state by secreting adiponectin...
BioCentury | Apr 7, 2017
Clinical News

BMS-986036: Ph II data

...respectively, vs. 1.3%, p=0.0004 and p=0.008). Both doses of BMS-986036 also improved magnetic resonance elastography, adiponectin...
BioCentury | Mar 24, 2017
Strategy

Connecting in Kyoto

...insulin resistance, dyslipidemia and glucose intolerance, and increases survival in mouse models of diabetes. The adiponectin (ADIPOQ)...
...clinical development that target the ligand or its receptors. One reason is that synthesizing recombinant adiponectin...
BioCentury | Mar 16, 2017
Targets & Mechanisms

Bone appétit!

...with adipose tissue to stimulate production of the insulin sensitizer ADIPOQ . Both insulin and ADIPOQ...
...renal phosphate excretion . Unlike LCN2 and osteocalcin, FGF23 does not affect appetite. ADIPOQ - Adiponectin...
BioCentury | Nov 19, 2016
Strategy

Adding on in fibrosis

...sensitivity and HDL, while also lowering LDL and triglycerides. But Burgess noted it also increased adiponectin...
BioCentury | Oct 20, 2016
Translation in Brief

Killer burn

...as much weight as their wild-type counterparts, and had less fat browning and FGF21 and adiponectin (ADIPOQ)...
BioCentury | Apr 11, 2016
Clinical News

Subcutaneous beloranib: Additional Phase III data

...in hyperphagia-related behaviors and total body weight at week 26; changes in LDL-C, HDL-C, triglycerides, adiponectin...
BioCentury | Mar 10, 2016
Distillery Therapeutics

Therapeutics: Adiponectin (ADIPOQ)

...Genitourinary disease INDICATION: Polycystic ovary syndrome (PCOS) Rat studies suggest promoting brown fat activity with ADIPOQ...
...levels of ADIPOQ compared with skeletal muscle transplants or no tissue transplants. In the model, ADIPOQ...
...libraries to identify agents that induce brown fat activity or differentiation in PCOS models. TARGET/MARKER/PATHWAY: Adiponectin (ADIPOQ)...
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