BioCentury | Jan 16, 2014
Distillery Therapeutics

Indication: Cancer

...contact information Cancer Cancer Adhesion regulating molecule 1 (ADRM1; RPN13) In vitro and mouse studies suggest inhibiting the RPN13...
...cancer. In vitro, a bis-benzylidine piperidone bound to the pleckstrin-like receptor for ubiquitin domain of RPN13...
BioCentury | Jan 16, 2014
Targets & Mechanisms

Putting a lid on cancer cell proteasomes

...by a 19S regulatory particle. The regulatory particles contain RPN10 and adhesion regulating molecule 1 ( ADRM1 ; RPN13...
...the RPN13 subunit of the regulatory particle, since RA190 did not bind a mutant of RPN13...
...that Rpn13 is not an essential gene in mice. Goldberg said, "It is surprising that RPN13...
Items per page:
1 - 2 of 2