08:00 , Jan 16, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Adhesion regulating molecule 1 (ADRM1; RPN13) In vitro and mouse studies suggest inhibiting the RPN13 proteasomal component could help treat cancer. In vitro, a...
08:00 , Jan 16, 2014 |  BC Innovations  |  Targets & Mechanisms

Putting a lid on cancer cell proteasomes

Blocking the catalytic activity of proteasomes is a tried-and-true strategy in multiple myeloma, but use of marketed inhibitors is limited by drug resistance and lack of efficacy in solid tumors. Now, a team from The...