BioCentury | Mar 10, 2016
Distillery Therapeutics

Therapeutics: Tumor necrosis factor (TNF); adhesion G protein-coupled receptor E1 (ADGRE1)

...Hepatic disease INDICATION: Hepatic Mouse studies suggest a bispecific macrophage-targeting antibody against TNF and ADGRE1 could...
...TNF and the macrophage-specific receptor ADGRE1 increased survival compared with an anti-TNF antibody lacking the anti-ADGRE1...
...the bispecific antibody in models of TNF-driven inflammatory disease. TARGET/MARKER/PATHWAY: Tumor necrosis factor (TNF) ; adhesion G protein-coupled receptor E1 (ADGRE1)...
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