19:00 , Jan 4, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: December 2017

New Therapeutic Targets and Biomarkers: December 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during December 2017. Therapeutic targets are defined as any protein, gene or other molecule...
18:08 , Dec 20, 2017 |  BC Innovations  |  Distillery Techniques

Drug platforms

TECHNOLOGY: Gene therapy An ADARB2-based method of editing RNA could help treat diseases caused by point mutations, such as Rett syndrome and X-linked nephrogenic diabetes insipidus. The method repairs disease-associated G to A mutations in RNA...
08:00 , Nov 21, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Amyotrophic lateral sclerosis (ALS) Chromosome 9 open reading frame 72 (C9orf72) Studies...
08:00 , Nov 7, 2013 |  BC Innovations  |  Cover Story

ALS antisense oligonucleotides

Isis Pharmaceuticals Inc. has teamed up with a trio of academic groups to develop antisense therapeutics for the largest subset of patients with amyotrophic lateral sclerosis,1-3 and all three teams have converged on a common...