19:25 , May 6, 2019 |  BC Innovations  |  Distillery Therapeutics

ADORA2A identified as a thrombosis target

DISEASE CATEGORY: Cardiovascular INDICATION: Thrombosis Cell culture and mouse studies suggest agonizing ADORA2A could help treat thrombosis. In primary human and mouse neutrophils treated with IgG from patients with antiphospholipid syndrome (APS), which is associated...
01:04 , Jan 11, 2019 |  BioCentury  |  Finance

Exscientia looks inward

After spending six years building its artificial intelligence drug discovery platform and working with pharma partners, Exscientia Ltd. aims to use the bulk of the $26 million raised in a series B round to build...
03:21 , Nov 17, 2018 |  BioCentury  |  Product Development

Betting Combos on Biomarkers

Despite lackluster monotherapy data at SITC from the latest tranche of immunotherapy candidates, drug developers are moving into combination trials with PD-1 and PD-L1 inhibitors based on biomarkers of pharmacodynamic activity. Results from the next...
00:18 , Nov 17, 2018 |  BC Extra  |  Preclinical News

Spotlight co-founder uses CRISPR screen to ID T cell regulator genes for cancer

Spotlight Therapeutics Inc. (Hayward, Calif.) co-founder Alexander Marson and colleagues at University of California San Francisco developed a CRISPR-based screen to identify genes that control T cell replication and immunosuppression, and used the results to...
20:46 , Oct 19, 2018 |  BioCentury  |  Finance

Taiho ups its stakes

After bumping up its evergreen fund from $50 million to $300 million, Taiho Ventures LLC plans to increase its stakes in its portfolio companies. The strategic venture arm of Taiho Pharmaceutical Co. Ltd. launched in...
18:26 , Oct 19, 2018 |  BC Week In Review  |  Financial News

Taiho Ventures increases investment pool to $300M

Taiho Ventures LLC increased its investment pool to $300 million from $50 million. The firm said it will focus the additional funds on oncology startups with drug discovery capabilities or unique platform technologies. Taiho Pharmaceutical...
20:55 , Oct 16, 2018 |  BC Extra  |  Financial News

Taiho Ventures ups investments to $300M, to focus on oncology

Taiho Ventures LLC increased its investment pool to $300 million from $50 million. Taiho Ventures said it will focus the additional funds on oncology startups with drug discovery capabilities or unique platform technologies. Taiho Pharmaceutical...
18:24 , Aug 31, 2018 |  BC Week In Review  |  Clinical News

Kyowa's KW-6356 improves motor symptoms in Phase IIa for early PD

Kyowa Hakko Kirin Co. Ltd. (Tokyo:4151) said low- and high-dose oral KW-6356 both improved motor symptoms compared with placebo in a Phase IIa trial in 168 patients with early Parkinson's disease who had not received...
16:14 , Jul 20, 2018 |  BC Week In Review  |  Company News

Taiho exercises option for AB928

Taiho Pharmaceutical Co. Ltd. (Tokyo, Japan) exercised an option to develop and commercialize AB928 from cancer company Arcus Biosciences Inc. (NYSE:RCUS) in Japan and other Asian territories, excluding China. Arcus will receive an option exercise...
19:01 , Jun 22, 2018 |  BC Week In Review  |  Financial News

Oncology play iTeos raises $75M, outlines clinical plans

iTeos Therapeutics S.A. (Gosselies, Belgium) raised $75 million on June 19 in a series B round led by MPM Capital. Also participating in the round were HBM Partners, 6 Dimensions Capital, Curative Ventures and SFPI...