08:00 , Jan 27, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma Activating transcription factor 2 (ATF2) In vitro and mouse studies suggest that inhibiting ATF2 could help treat melanoma. In a transgenic mouse model of...
07:00 , Oct 30, 2008 |  BC Innovations  |  Targets & Mechanisms

Block JNK at the dock

A team of U.S. researchers has described a new mitogen-activated protein kinase 8 ( JNK ; MAPK8 ) inhibitor that targets JNK's substrate docking site-instead of its ATP binding site-to treat type 2 diabetes. 1...
08:00 , Feb 14, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Basal cell carcinoma (BCC); squamous cell carcinoma (SCC) Activating transcription factor 2 (ATF2) Studies in mice suggest that ATF2 functions as...